隐球菌性脑膜脑炎Cryptococcu

Meningoencephalitisn.脑膜脑炎

Photophobian.畏光

Flucytosinen.氟胞嘧啶

Fluconazolen.氟康唑

Ourimageinclinicalmedicinefeaturesa36-year-oldmanwhopresentedtotheemergencydepartmentwitha2-weekhistoryoffever,headache,drowsiness,andphotophobia.Hewaspreviouslyhealthyandwassexuallyactivewithmen.Thephysicalexaminationwasnotableforatemperatureof38.3°Candneckstiffness.CToftheheadwasnormal.Theopeningpressureonlumbarpuncturewas29cmofwater.Thecerebrospinalfluid(CSF)cellcountwascellspermicroliterwith90%mononuclearcells,whichwerepredominantlylymphocytes.Gram’sstainandIndiainkstainrevealedabundantencapsulated,roundyeasts,withsomebuddingforms.Thecryptococcalantigentiterwas1:,andtheCSFculturegrewCryptococcusneoformans.Atestforthehumanimmunodeficiencyvirusantibodywaspositive,andtheCD4+countwas7cellspermicroliter.InductiontherapywithliposomalamphotericinBandflucytosinewasstarted,andresolutionofsymptomsandnegativeresultsonCSFculturewerenotedafter2weeksoftreatment.Consolidationtherapywithfluconazolewasstartedandantiretroviraltherapywaslaterprescribed.1

临床医学图片刊载了一名36岁男性,因发热、头痛、嗜睡和畏光两周至急诊就诊。患者既往健康,与男性发生性行为。体格检查中,值得注意的是体温38.3摄氏度和颈强直。头部CT正常。腰穿初压为29厘米水柱。脑脊液细胞计数为细胞/微升,90%为单核细胞,主要是淋巴细胞。革兰氏染色和印度墨汁染色显示大量带荚膜的圆形酵母,有一些出芽。隐球菌抗原滴度为1:,脑脊液培养有新型隐球菌生长。HIV抗体检测呈阳性,CD4+细胞计数为7细胞/微升。给予脂质体两性霉素B和氟胞嘧啶开始诱导治疗,两周后患者症状缓解并且脑脊液培养为阴性。给予氟康唑进行巩固治疗,而后开始抗病毒治疗。

1.医学单词记忆

-coccus构词成分球菌

Cryptococcusn.隐球菌

Diplococcusn.双球菌

Gonococcusn.淋球菌

Enterococcusn.肠球菌

Meningococcusn.脑膜炎球菌

Pneumococcusn.肺炎球菌

Streptococcusn.链球菌

Staphylococcusn.葡萄球菌

食物中毒FoodPoisoning

2.常用医学词组

Cryptococcusneoformans新型隐球菌

neckstiffness颈强直

lumbarpuncture腰穿

cerebrospinalfluid脑脊液

cellcount细胞计数

Gram’sstain革兰氏染色

Indiainkstain印度墨汁染色

humanimmunodeficiencyvirus

人类免疫缺陷病毒

HIV相关癌症和疾病HIV-AssociatedCancersandRelatedDiseases

CD4+countCD4细胞计数

amphotericinB两性霉素B

3.常用英语表述方式

1)体温38.3摄氏度

表述为thirty-eightpointthreedegreesCelsius

或者表述为thirty-eightpointthreedegreesCentigrade

2)细胞/微升

表述为threehundredandfortycellspermicroliter

3)29厘米水柱

表述为twenty-ninecentimetresofwater

Cryptococcusneoformansisafungusthatlivesintheenvironmentthroughouttheworld.Peoplecanbe







































治疗白癜风多少钱
北京治疗白癜风哪家医院安全



转载请注明:http://www.ruishiccguanwang.com/xxyqjxnmywh/3603.html


当前时间: